The Glenn was later scuttled, though Ripper was beamed to Discovery and secured within that ship's own spore drive assembly. ( DIS: " Context Is for Kings", " The Butcher's Knife Cares Not for the Lamb's Cry") However, soon after, the crew of the Glenn hit a Hawking radiation firewall while exiting the mycelial plane, causing the death of its crew. The Glenn managed to travel back and forth into the Beta Quadrant, a ninety light year jump, in 1.3 seconds. Emboldened by the breakthrough, Straal reported that he was going to attempt Speirin 900, even though Stamets was concerned about the feasibility and safety of such a massive displacement. These abilities resulted in its function as a sort of "navigator" for the Glenn. The fact that they did not grow their own spores somehow resulted in the acquisition of " Ripper", an alien creature resembling an Earth tardigrade that lived in some kind of symbiosis with the spores and was capable of communicating with them, as well as utilizing the mycelial network. However, its sister ship Glenn made a breakthrough and achieved Speirin 240. This was considered a poor result by Discovery captain Gabriel Lorca. Some six months after the start of the war, the Discovery had reached Speirin 12, and leaps measured in the hundreds of kilometers. The two ships lacked the processing power to make the requisite number of calculations, and so long jumps resulted in navigational instability. Jumping was probabilistic, meaning that the longer the jump, the more possible outcomes there were. Key to the research was to increase the interval, which was expressed in Speirin, higher Speirins being associated with large displacement. ![]() Containment of the spores was important to prevent accidents. These jumps were associated with the ship's walls becoming damp. The Discovery also contained a large cultivation bay.īy late 2256, six months after the start of the war, both ships were conducting " black alert" maneuvers, in which they made jumps across the mycelial network. The two scientists were split up and given two different teams on different vessels - the USS Discovery and the USS Glenn - so, they could work twice as fast. Initially confined to a lab, following the outbreak of war with the Klingons, Starfleet co-opted the research for military applications, much to the displeasure of Stamets. The USS Discovery helm with spore drive activation control Feel free to edit this page to assist with this expansion. Information regarding expansion requirements may be found on the article's talk page. Together, the mechanisms controlling sigma factor activity ensure that genes are expressed at the proper time and level in each cell type.This article or section is incomplete This page is marked as lacking essential detail, and needs attention. Negative feedback loops limit sigma factor production and facilitate the transition from one sigma factor to the next. Accessory transcription factors modulate RNA polymerase activity at specific promoters. Other mechanisms, such as an anti-sigma factor and, perhaps, proteolytic degradation, prevent sigma factors from becoming active in the wrong cell type. This signalling can result in proteolytic sigma factor activation. These bifunctional proteins, as well as other proteins involved in sigma factor activation, and even precursors of sigma factors themselves, are targeted to critical locations, allowing the mother cell and forespore to communicate with each other and to co-ordinate their programmes of gene expression. ![]() In some cases, novel proteins control both sigma factor activity and morphogenesis, co-ordinating the programme of gene expression with morphological change. The activity of each sigma factor in the cascade is carefully regulated by multiple mechanisms. At the heart of the programme are sigma factors, which become active at different times, some only in one cell type or the other, and each directing RNA polymerase to transcribe a different set of genes. Driving these changes is a programme of transcriptional gene regulation. ![]() The larger mother cell engulfs the smaller forespore, then nurtures it and, eventually, lyses to release a dormant, environmentally resistant spore. When starved, Bacillus subtilis undergoes asymmetric division to produce two cell types with different fates.
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